Quizzes

Which of the following feature in Crohn’s disease is seen in smokers?

A 22-year-old patient presents with weight loss and bleeding per rectum. You organise a flexible sigmoidoscopy.

Which of the following histological features would favour a diagnosis of Crohn’s disease and not ulcerative colitis?

Which one of the following features seen on barium studies is present in both ulcerative colitis and Crohn’s disease?

A 22-year-old woman returns from her gap year travels with low grade fever, intermittent abdominal pain and diarrhoea. She has been feeling unwell for 2 months and has returned to the UK because she has begun to lose weight. Her only medication is the combined oral contraceptive pill. On examination, there is pallor, her BP is 110/60 mmHg, pulse is 75, and her BMI is 18 kg/m2. Her abdomen is soft, but she complains of right-sided abdominal pain. Investigations show Hb 108 g/L (115‐165) WCC 9.2 ×109/L (4‐11) PLT 206 ×109/L (150‐400) CRP 74 mg/L (<10) Na 138 mmol/L (135‐146) K 4.8 mmol/L (3.5‐5) Cr 120 μmol/L (79‐118) Colonoscopy reveals areas of discrete ulceration identified, punctuated by normal mucosa. The biopsy reveals transmural non-caseating granulomata. What is the most likely diagnosis?

A 31-year-old man presents with anaemia, bleeding tendency, abdominal pain and persistent diarrhea. Examination reveals a palpable mass in the right iliac fossa and anal skin tags.

What is the most likely underlying condition?

Which of the following extra-intestinal features is most commonly associated with ulcerative colitis?